Joint support for cartilage, mobility & recovery
Move freely. Train longer. Age slower.
Joint+ is a natural joint support supplement built on IPH-AEN — a patented, NSF Certified for Sport® peptide that signals your body's own cartilage-building genes. No injections, no synthetics. Just clean, targeted joint support in a daily oral capsule.
Natural joint support supplement for cartilage regeneration, comfortable mobility, and long-term joint health.
* Most noticeable results after 90 days
** Applies for first purchase only
ACTIVE INGREDIENT
(PATENTED PEPTIDE)
CERTIFIED FOR SPORT®
290+ SUBSTANCES SCREENED
INJECTIONS.
ORAL CAPSULE ONLY.
Comfort you notice when it's gone
You don't feel your cartilage repairing itself — you feel it when it doesn't. Joint+ supports the biology behind comfortable movement, so stiffness and wear don't quietly compound year over year.
Upregulates COMP and COL2A1, the two genes primarily responsible for cartilage collagen synthesis.
In a rat hip-socket injury model, viable tissue area increased 2.7× versus controls.
Increases MMP13, the enzyme governing cartilage matrix turnover, by up to 9.6× in cell research.
In an 88-patient study, pain scores (VAS) improved 1.4× over six months, with reduced cartilage thinning.
Joint support that signals, not just supplies
Most joint supplements deliver raw building blocks and hope your cells use them. IPH-AEN works upstream — a short-chain peptide that switches on the genes that build cartilage. Think bricks vs. the instruction to build. Dosed in micrograms, not grams.
SOURCES — NCBI GENE: COMP #1311 · COL2A1 #1280 · MMP13 #4322 · SLC15A1 #6564 · NIH NIAMS · IVKO X. ET AL., DANISH SCIENTIFIC JOURNAL NO. 26, 2019.
Tissue-specific. Gene-level. Oral.
Unlike conventional supplements that work loosely across the body, IPH-AEN is matched to cartilage and connective tissue — and targets only the gene pathways specific to it.
One patented peptide. Nothing extra.
Servings per container: 30
Made for anyone who's put miles on their body
Joint+ is for people whose movement is limited by how their joints feel, not by effort.
From ultramarathons to martial arts
Athletes who have pushed the limits of human performance, for decades. Their common thread: they want what works — and they're willing to interrogate the evidence before they trust a product.
50 marathons in 50 states in 50 consecutive days. 350 miles nonstop. A race across Death Valley. A marathon to the South Pole. TIME's 100 Most Influential People. Victories at Badwater and the 4 Deserts Challenge — on all seven continents.
50 marathons in 50 states in 50 consecutive days. 350 miles nonstop. A race across Death Valley. A marathon to the South Pole. TIME's 100 Most Influential People. Victories at Badwater and the 4 Deserts Challenge — on all seven continents.
Training since age four across more than 20 martial arts styles. His fighting was motion-captured for Mortal Kombat. He trains 5–6 hours a day, seven days a week. Starting strong on Monday is easy — still going hard on Friday demands a different kind of preparation.
Starting strong on Monday is easy. Still going hard on Friday — that takes something more. Muscle+ keeps my recovery honest. Thejumping, flipping, landing, the bag work, the weight training: it all adds up. Joint+ handles my joints, Muscle+ handles everything else."
U.S. National Chess Master at 17. 2025 Super Heavyweight Chessboxing World Champion — winning the title in Serbia. A Detroit native whose career demands peak mental and physical performance simultaneously.
I have so much more energy, and especially on a full night's sleep. I have a noticeable difference in my ability to push through long days. My focus is sharper, my thoughts are clearer — and in chessboxing, where you need both your body and your mind firing, that edge is everything."
Mobility you can count on.
No needles, no refrigeration, no excuses.
One oral capsule, NSF Certified for Sport® — a daily habit built to support the joints that carry you through everything else you do.
Every claim is earned
Independently screened for 290+ banned substances. Trusted by professional athletes whose careers depend on what they put in their bodies.
Derived from non-scaly marine fish via a patented extraction process. No bovine, porcine, or synthetic inputs. Pareve-friendly. Gluten, dairy, and soy free.
Pürblack is the only company in the United States licensed to manufacture with the IPH-AGAA peptide. You cannot get this exact compound from any other US brand.
Produced in a US facility with comprehensive heavy-metal and microbiological testing. No additives, no unnecessary fillers.
Two levels of testing.
Full transparency.
Every batch carries an independent NSF lab certificate and our own comprehensive internal COA. If we make a claim, you can read the paperwork behind it.
Simple by design.
Precise by science.
These are signalling molecules, not substrates. You don't need large volumes — the precision of the signal matters, not the quantity. Consistent daily use is key; the ingredient works gradually as part of your body's own biological rhythms.
What customers are
saying
FAQ
A short-chain, marine-derived peptide that signals cartilage cells to activate COMP and COL2A1 — the genes responsible for cartilage collagen production — and supports healthy matrix remodelling via MMP13.
Those approaches supply raw material and rely on your body to use it. IPH-AEN sends a direct signal to the genes that build cartilage, dosed in micrograms rather than grams.
No. Joint+ is a daily oral capsule, absorbed via the PepT1 transporter.
Yes — Joint+ is NSF Certified for Sport®, independently screened for 290+ banned substances.
Marine-derived and pareve-friendly; no bovine or porcine inputs.
Cartilage remodelling is gradual. Clinical research on IPH-AEN measured meaningful pain and mobility improvements over a 3–6 month period of consistent daily use.
Yes — Joint+ pairs with shilajit resin or other Pürblack peptides (e.g., Muscle+) without overlap.
Orders ship from our US facility with tracked delivery. See the Shipping page for current rates and timelines.
Natural joint support supplement for cartilage regeneration, comfortable mobility, and long-term joint health.
* Most noticeable results after 90 days
** Applies for first purchase only
Support the joints that
carry everything else.
Joint+ contains IPH-AEN, an independently certified, patent-protected peptide ingredient with a published body of research. NSF Certified for Sport®. No injections. No synthetics.
NSF Certified for Sport® · Marine-derived · Oral capsule · No injections