The runner’s problem set (and why ultras are different)

Two people running on a road with a natural landscape in the background
  • High mileage & doubles drive mitochondrial stress, micro-tears, and central fatigue.
  • Hills & descents add heavy eccentric loading to quads, calves, and connective tissues.
  • Back-to-back long runs & ultras (50K–100M) stack hours on feet, glycogen depletion, GI strain, sleep/circadian disruption, inflammation, and electrolyte/vascular challenges.
  • Race travel, heat, altitude increase oxidative stress and immune load.

Translation

You don’t just need calories—you need cellular energy efficiency, faster muscle/tendon repair, robust connective tissue turnover, calm inflammation, reliable circulation, and deep sleep architecture that actually restores you.

What the body needs to keep stacking quality miles

Mitochondrial output & efficiency

  • Better mitochondrial quality control (mitophagy/autophagy) to clear damaged mitochondria.
  • Support for ATP production to maintain pace late in workouts/races.
  • Metabolic flexibility to spare glycogen and reduce perceived exertion.
Muscles

Muscle repair & soreness control

  • Rapid activation of muscle protein synthesis pathways for micro-tear repair.
  • Eccentric-damage mitigation (downhill, strides, intervals).
  • Less DOMS so intensity can repeat.
Cartilage

Tendon, ligament & joint durability

  • Support collagen synthesis, cartilage ECM (proteoglycans, hyaluronic acid).
  • Healthy inflammation resolution without blunt over-suppression.
  • Targeted nourishment for Achilles, patellar tendon, knees/ankles/hips.
Veins

Circulation & oxygen delivery

  • Smooth vascular tone for steady pacing and thermoregulation in heat/altitude.
  • Micro-circulatory support for tissues under repetitive load.
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Sleep & immune resilience

  • Downshift sympathetic drive for deeper SWS/REM after hard blocks.
  • Immune readiness during peak weeks/travel to avoid lost training days.
Woman running on a trail with a scenic background

What does it mean for you?

As an ultra runner, your limiter isn’t grit—it’s whether your body can keep turning training into adaptation day after day. You need efficient cellular energy so pace doesn’t fall apart late, faster muscle repair to handle eccentric damage and keep soreness from lingering, and durable tendons, ligaments, and joints that stay quiet under repetitive load. You also need strong circulation for oxygen delivery, heat/altitude management, and tissue nourishment—plus truly restorative sleep and immune resilience so you can recover from big blocks and keep stacking quality miles without missed days.

How Pürblack works as a system

Two black containers with 'White Rabbit' branding on a light gray background

Morning (Activation & Energy Economy)

Research Grade shilajit Resin (AM)
  • Rich in ashless humic acids, fulvic acids, and 80+ bioactive minerals supporting the urolithin-A pathway—linked to mitophagy and improved mitochondrial efficiency.
  • Promotes clean, stimulant-free ATP production and steadier perceived energy for long rides and pre-run bricks.
Optional AM variant — White Rabbit® Vive
  • Introducing White Rabbit Shilajit Resins—our advanced shilajit infused with subtle, natural flavors and aromas for an enhanced experience… Enjoy the journey to peak performance with a touch of flavor.
  • Use when you want gentle AM activation with a smoother sensory profile.
Three supplement containers labeled 'BCAA', 'Muscle+', and 'Vascular+' on a white background.

Post-session / Midday (Repair & Flow)

Muscle+ Peptide Capsules (NSF Certified for Sport®)
  • Targeted peptides to support muscle regeneration pathways and reduce post-effort fatigue, helping you turn quality again within 24–48 hours.
Vascular+ Peptide Capsules
  • Supports vascular tone and micro-circulation to clear metabolites and reduce between-session stiffness—useful after downhill or interval stress.
Two dietary supplement containers labeled 'Joint+' and 'Serene' on a light gray background.

Evening (Downshift & Deep Repair)

White Rabbit® Serene shilajit Resin (PM)
  • Adaptogenic evening resin to promote nervous-system downshift, sleep quality, and overnight hormonal balance so tissues actually rebuild while you rest.
Joint+ Peptide Capsules (NSF Certified for Sport®)
  • Targets cartilage anabolism and connective-tissue nutrition to support knee/ankle/hip durability when volume and vert rise.

Science notes

Urolithin-A & mitophagy: our shilajit contains an increased amount of urolithin-A, which is associated with activation of mitophagy—the cell’s cleanup of damaged mitochondria—leading to improved muscle endurance, reduced fatigue, and better energy economy you can feel in long efforts.

Fulvic/humic matrix: facilitates mineral transport and redox balance that support mitochondrial enzymes involved in ATP production—useful when glycogen runs low.

Peptide signaling (Muscle+): short-chain peptides can nudge muscle protein synthesis and repair pathways, helping restore force production after eccentric loading.

Joint & ECM support (JointT+): designed to support collagen/hyaluronan dynamics and the cartilage extracellular matrix, key for runners’ repetitive load.

Vascular tone (Vascular+): supports endothelial function and flow, aiding nutrient delivery and heat dissipation on long, hot, or high-altitude days.

Sleep architecture (Serene): better parasympathetic balance at night → deeper SWS/REM → more complete muscle/connective tissue repair.

These mechanisms describe supportive physiology and are not medical claims. Always follow your physician’s guidance.

Protocols for athletes

Base Mileage (steady build, 40–70 mi/wk)

AMResearch Grade (or Vive)

Midday: Muscle+

PM: Serene and Joint+

Add: JOINT+ if >50 mi/wk or history of knee/Achilles issues

Peak Block / Race Prep 
(4–8 weeks, road or trail)

AM: Research Grade

Midday: Muscle+ & Vascular+ (post-workout)

PM: Serene & Joint+

Why: Higher ATP demand, more eccentric damage, deeper nightly rebuild

Downhill & Ultra Defense (vert blocks, 50K–100M)

AM: Research Grade

During Block: Muscle+ & Joint+ daily

PM: Serene; add Vascular+ after long downhill sessions

Why: Protect quads/tendons, sustain output on fatigued legs, improve next-day function

Heat / Altitude / Travel Weeks

AM: Research Grade

Midday: Vascular+

PM: Serene

Plus: Immunity Max per label for race-travel resilience

Base Mileage (steady build, 40–70 mi/wk)

AMResearch Grade (or Vive)

Midday: Muscle+

PM: Serene and Joint+

Add: JOINT+ if >50 mi/wk or history of knee/Achilles issues

Peak Block / Race Prep 
(4–8 weeks, road or trail)

AM: Research Grade

Midday: Muscle+ & Vascular+ (post-workout)

PM: Serene & Joint+

Why: Higher ATP demand, more eccentric damage, deeper nightly rebuild

Downhill & Ultra Defense (vert blocks, 50K–100M)

AM: Research Grade

During Block: Muscle+ & Joint+ daily

PM: Serene; add Vascular+ after long downhill sessions

Why: Protect quads/tendons, sustain output on fatigued legs, improve next-day function

Heat / Altitude / Travel Weeks

AM: Research Grade

Midday: Vascular+

PM: Serene

Plus: Immunity Max per label for race-travel resilience

Why Pürblack as a system (not just a supplement)

  • Inputs → Processing → Outputs:
    Minerals & shilajit resins (input) improve transport and mitochondrial processing; peptides (process) signal repair/regeneration; result (output) is more repeatable quality and less next-day cost.
  • AM/PM orchestration:
    Activation when you need it; downshift when you must—recovery is programmed, not left to chance.
  • Stack synergy:
    Urolithin-A–linked mitophagy + peptide-driven repair + vascular flow + sleep depth = a closed loop that supports the exact stressors runners face.

Athletes Stories

Dean Karnazes

Dean is a globally recognized American ultramarathon runner, endurance athlete, and bestselling author who has redefined the limits of human potential. He’s known for extraordinary feats such as running 50 marathons in 50 U.S. states in 50 consecutive days, completing 350 miles nonstop, racing across Death Valley in extreme heat, and running a marathon to the South Pole. A TIME “100 Most Influential People in the World” honoree and multiple award-winner in elite endurance events, including victories at the Badwater Ultramarathon and the 4 Deserts Challenge, Dean has competed on all seven continents and inspired athletes around the globe with his relentless pursuit of adventure and resilience.

In addition to his athletic legacy, he’s a New York Times bestselling author, speaker, and advocate for health, movement, and human performance. Dean has been using Pürblack shilajit resins and peptides to help with his training and recovery since 2025./products/joint-peptide

Product Uses:

Peptides: Brain PM, Brain AM, Muscle+, Joint+

White Rabbit: Vive

FAQ

  • Running & Ultramarathon
  • Shipping & Orders
  • Subscriptions
  • Return, Refund & Replacements
Is this for ultramarathons only? +

No. It’s for serious runners from 5 Miles PR chasers to 100-milers—anyone stacking quality and volume.

Can I use Vive instead of Research Grade in the morning? +

Yes—choose Vive for a smoother sensory profile and gentle AM activation; Research Grade when you want a more neutral AM resin.

Can I combine MUSCLE+ and JOINT+? +

Yes—many runners do during hills/vert or race prep blocks.

What about heat or altitude races? +

Add Vascular+ for flow/thermoregulation support and consider Immunity Max for travel/race weeks.

Is this NSF-certified? +

MUSCLE+ and JOINT+ are NSF Certified for Sport®.

When will my order be shipped? +

Orders take 1-2 business days to process and are shipped promptly. We do not ship orders during the weekend or during US holidays.

Orders are confirmed when they get a tracking number.

How do I track my order? +

Orders take 1-2 business days to process and are shipped promptly. We do not ship orders during the weekend or during US holidays.

Orders are confirmed when they get a tracking number.

How do I track my order? +

Use our chat box to track your order or get updates directly from your email. Order updates are sent to your registered email and will have a tracking link available.

Where can I find my order number? +

You can find your order number in the order notification sent to you via email.

How much do you charge for shipping? +

All orders shipped to the USA are shipped free.

For overseas orders, order weight and location determine the shipping rates in real time.

You can check for shipping rates by adding the product you like to the cart, then proceed to checkout.

In the checkout, add in your address and allow the page to get real time shipping rates.

UPS, DHL and USPS handle domestic USA shipping and UPS, DHL and USPS for international shipping.

Customs fees and charges are not included in the shipping offer.

At this time, due to custom regulations we are unable to ship to Mexico

Do you cover customs fees and charges? +

Shipping cost does not include the majority of customs fees and charges.

Failure to pay customs fees required to complete delivery may result in your package being abandoned by the courier. No refund will be issued for abandoned items.

Packages that are refused delivery or are returned for other reasons will incur return fees and may no longer qualify for a full refund.

Can I still change my address after my order is shipped out? +

No, you cannot, but you can ask the courier to intercept your package. The courier will hold your package awaiting further instructions. Please call the courier service for more details.

What if I didn't receive my order and the status says returned to sender? +

A problem in your address or that the package cannot be delivered could be the reason for why it was returned. To reship your order, we need the payment of a return fee + new shipping fees whenever applicable.

Return fees are fees charged by UPS for orders returned to us and vary depending on the size and weight of the order.

If my order/shipment states return to sender, can I get a refund instead? +

We can refund upon payment of the return fee. The fee can be deducted from the total amount available for refund.

If my order arrived damaged or broken, what should I do? +

Contact us soon as possible for assistance and provide all necessary files and documents:

  • Receipt or invoice
  • Photos of your package and contents
  • Shipping label posted on the box
  • The documents included in the shipment if any
  • Photos of the Items broken
  • Any other relevant information

We can reship you the broken or damaged order or you can also file a claim with the courier service if your order arrived damaged to recover the value of the broken order. We are happy to assist you in all courier claims as best as we can.

If my package is missing an item what should I do? +

Contact us soon as possible for assistance and provide all necessary files and documents.

  • Receipt or invoice
  • Detailed photos of your package. Include photos of your package in its current condition.
  • Shipping label
  • Documents included in the shipment clearly that clearly identify the contents and what is expected

We can ship you the missing items or you can also file a claim with the courier service if your order arrived damaged. We are happy to assist you in all courier claims as best as we can.

What are subscriptions? +

Subscriptions are recurring discounted monthly orders. They allow you to automate delivery and maintain your supply for a discounted cost and are the perfect option if you need a guaranteed supply of your product.

How do I manage my subscription? +

A link is provided in the subscription confirmation email allowing you access to your customer portal. You can update your address, skip or change order dates, add, remove or swap products in the subscription, and many more.

If I want to cancel a subscription order what do I do? +

You can cancel your subscription at any time before the order is dispatched and the tracking number assigned.

You will be notified five days in advance of a scheduled order being dispatched.

Access your customer subscription portal and modify or change your next order date accordingly. If you need assistance, please contact us.

How do I change my payment information? +

Log-in to your customer portal and change your payment details. If you need assistance, please contact us.

How do I skip the next order? +

Access your customer portal to make edits to your subscription.

Can I change my order frequency? +

Yes, you can change your order frequency between 30 days and 60 days. If you'd like to make this change, please contact us at purblack.com/contact-us

Can I change the items in my order? +

Yes you make adjustments to the products in your subscriptions for eligible products.

What is your return policy? +

Returns are allowed within 30 days of delivery. Some conditions apply.

Initiate the return process by submitting a request through our Contact Us page.

For hygiene reasons, your item must meet certain criteria to qualify for a return. It should be in its original condition, unopened, unused, and in the original packaging.

Additionally, a valid receipt or proof of purchase.

What is your refund policy? +

Upon receiving and inspecting your return, we will notify you of the approval. If approved, a refund will be automatically processed to your original payment method. Keep in mind that it may take some time for your bank or credit card company to complete the refund transaction.

Any returns fee due an order will be deducted from the final refund amount.

Make your training count

Use the Runner’s Stack daily, layer Vascular+/Immunity during stress windows, and keep Serene nightly during peak blocks. Your plan: more quality sessions, less cost to the body, and a better start line.